Analysis of Factors That Influence Cognitive Impairment in Older Adults With Cardiovascular Disease in Guangdong Province, China |
| Min Peng Yi Zhang Xiaoxia Wang Qiao Huang Jinhua Guo Bei Gong Tiemei Shen |
| 1.Institute of Geriatrics, Guangdong Provincial People's Hospital(Guangdong Academy of Medical Sciences), Southern Medical University, Guangdong, Guangzhou, 510080, China;2.Institute of Cardiovascular Disease,Guangdong Provincial People's Hospital(Guangdong Academy of Medical Sciences),Southern Medical University, Guangdong, Guangzhou, 510080, China;3.Department of Nursing, Guangdong Provincial People's Hospital(Guangdong Academy of Medical Sciences),Southern Medical University, Guangdong,Guangzhou,510080,China |
Abstract ： Objectives With the aging population in China, the cognitive function of older adults has become a concern. However, few studies have evaluated the risk factors for changes in cognitive function in older adults with cardiovascular disease in China. Methods We conducted a population-based cross-sectional study of 3, 270 participants using a multistage, stratified, cluster-sampling procedure. Binary and multiple logistic regression analyses were used to explore the factors influencing cognitive impairment. Results The prevalence of cognitive impairment in older adults with cardiovascular disease was 27.7%, which was higher than that in the general older adult population. Multivariate regression analyses revealed that age (OR: 1.023; 95% CI: 1.011, 1.036), educational level (primary school or below: OR: 0.150; 95% CI: 0.094, 0.239; junior high school: OR: 0.258; 95% CI: 0.170, 0.392), monthly family income (RMB2, 000-4, 000: OR: 2.618; 95% CI: 1.949, 3.517; RMB4, 000-6, 000: OR: 1.809; 95% CI: 1.413, 2.316), place of residence (rural region or towns: OR: 0.665; 95% CI: 0.524, 0.843; small or mid-sized cities: OR: 0.710; 95% CI: 0.539, 0.936), medication usage, frequency of social activities, care from family or friends (OR: 1.420; 95% CI: 1.135, 1.777), hearing ability (OR: 0.754; 95% CI: 0.618, 0.920), walking ability (OR: 0.479; 95% CI: 0.387, 0.591), and symptoms of anxiety and depression were all significantly associated with cognitive impairment. Conclusion The high prevalence of cognitive impairment among older adults with CVD underscores the urgent need for integrated care models that address both cardiovascular and cognitive health. A comprehensive and systematic prevention and treatment program should be developed, incorporating early screening, multidisciplinary collaboration, and tailored interventions targeting the identified modifiable risk factors. Future longitudinal studies are needed to confirm these associations and explore underlying mechanisms.
Keywords chinese older adults; cardiovascular disease; cognitive function; cognitive impairment; cross-sectional study
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Conflict of Interest
The author declares no conflict of interest.
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